uracil$88859$ - tradução para alemão
CHEMICAL COMPOUND
Uracil mustard; C8H11Cl2N3O2; Aminouracil Mustard; Chlorethaminacil; Demethyldopan; Desmethyldopan; Nordopan; Uracil nitrogen mustard; Uracillost; Uracilmostaza; Uramustin
uracil
n. Urazil (chem. Verbindung, die die Biochemie-Forschung dient)
Definição
uracil
['j??r?s?l]
¦ noun Biochemistry a compound found in living tissue as a constituent base of RNA (and replaced by thymine in DNA).
Origin
C19: from ur(ea) + ac(etic) + -il.
Wikipédia
Uramustine
Uramustine (INN) or uracil mustard is a chemotherapy drug which belongs to the class of alkylating agents. It is used in lymphatic malignancies such as non-Hodgkin's lymphoma. It works by damaging DNA, primarily in cancer cells that preferentially take up the uracil due to their need to make nucleic acids during their rapid cycles of cell division. The DNA damage leads to apoptosis of the affected cells. Bone marrow suppression and nausea are the main side effects.
Chemically it is a derivative of nitrogen mustard and uracil.
